Subject: UF Radiology Research Newsletter – April Highlights (Publications of the Month)
Dear Colleagues,
We are pleased to share this month’s notable publications from the Department of Radiology at the University of Florida. Below are the April Publications of the Month (POM), each accompanied by a brief summary and a direct link for easy access.
- High Prevalence of Metabolic Dysfunction-Associated Steatohepatitis With Significant Fibrosis in Primary Care and Endocrinology Clinics
Journal: Diabetes, Obesity and Metabolism
🔗 DOI: 10.1111/dom.70799
https://pubmed.ncbi.nlm.nih.gov/42056678/
This study demonstrates a high prevalence of metabolic dysfunction-associated steatohepatitis (MASH) with clinically significant fibrosis among patients seen in primary care and endocrinology clinics. The findings underscore the substantial burden of undiagnosed advanced liver disease in individuals with obesity, type 2 diabetes, and metabolic syndrome.
The authors emphasize the importance of early screening and noninvasive fibrosis assessment in high-risk populations, particularly within frontline outpatient settings where metabolic disease is commonly managed. The work supports broader implementation of multidisciplinary strategies aimed at earlier detection and intervention to reduce progression to cirrhosis and liver-related complications.
- The Fatty Pancreas: Current Evidence, Treatment Implications, and Future Directions
Journal: Gastro Hep Advances
🔗 DOI: 10.1016/j.gastha.2026.100933
https://pubmed.ncbi.nlm.nih.gov/42027703/
This review explores the emerging clinical significance of fatty pancreas disease, summarizing current evidence regarding its association with obesity, diabetes, metabolic syndrome, pancreatitis, and pancreatic cancer. The authors discuss proposed mechanisms underlying pancreatic fat accumulation and its potential role in endocrine and exocrine dysfunction.
The paper also highlights evolving diagnostic approaches, imaging considerations, and therapeutic implications, emphasizing the need for standardized definitions and longitudinal studies. As interest in ectopic fat deposition continues to grow, this review positions fatty pancreas as an increasingly important topic in metabolic and gastrointestinal research with significant implications for future patient care.
- Development of a Prognostic Prediction Model for Clinically Significant Prostate Cancer Based on Lesion Zone and Apparent Diffusion Coefficient Value Quantification
Journal: Urology
🔗 DOI: 10.1016/j.urology.2026.01.028
https://pubmed.ncbi.nlm.nih.gov/41616920/
This study presents a prognostic model for clinically significant prostate cancer that incorporates lesion zonal anatomy and quantitative apparent diffusion coefficient (ADC) values derived from prostate MRI. By integrating imaging biomarkers with lesion location, the authors aim to improve risk stratification and diagnostic precision in patients undergoing prostate cancer evaluation.
The findings suggest that ADC quantification combined with lesion zone assessment may enhance prediction of aggressive disease, potentially supporting more personalized clinical decision-making and reducing unnecessary biopsies. The work highlights the growing role of advanced MRI analytics in refining prostate cancer diagnosis and management.
We congratulate all authors for their outstanding contributions and look forward to continued innovation in the months ahead.
Kind regards, UF Radiology Research Division